why do i feel worse after my b12 injection

Like it needs to be sorted because its affecting my everyday life. By clicking Accept, you consent to the use of ALL the cookies. I thought I would feel better straight away, but I suspect Ive been low for years, and so it make sense that recovery might take time! People may lose patience as you sort it all out, but take all the time you need to stay well. Hydroxocabalamin starts to work straight away. Her current doctor tested her for B12 deficiency only after my daughter, very insistently, asked her to do so. So I was wondering if theres any conditions that may affect this? Yep! The Many Faces of Cobalamin (Vitamin B12) Deficiency. I feel like I can set myself a realistic expectation for my treatment now. I? Recently I? I now see improvement in some of my symptoms for a while but I quickly go back to how I originally felt if I have something like a headache or have missed a vitamin. Fatigue, dizziness, paleness, and a rapid heart rate. According to the medical site Drug3K, B12 injections should be stored at a stable temperature of between 59 and 86 degrees Fahrenheit. Normally even high dose B6 complexes are not allowed to provide B6 over 25mg, which is the tolerable upper limit. Im a lot more out of breath and experiencing dizziness. Looking here on the PA forums is good, too! I haven't felt much of a change in my migraines, but have noticed that I just haven't been feeling well overall on a day to day basis. Again, in my case, it's my son. I cant do much until I have some sort of diagnosis so I can sort myself out. Hi Quinny99 - how are you feeling now?I experience a huge spike in symptoms after an injection too. For subcutaneous injections, pinch the fat and insert the needle into the fat under the skin. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. What are the signs and symptoms of a vitamin B12 deficiency? I have MTHFR mutation and wonder if this might be why they are not having a good effect on me. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. August 21, 2022 by Sandra Hearth. An abnormal increase in red I have had crying episodes that I did not have beforeso this vitamin injection did me little good. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Almost immediately, I developed swollen, painful sores that were identified as. I dont think my actual iron levels are low and the doctor said that I am not anaemic. Though rare, this reaction can cause muscle cramping, I know Im lucky to feel like this but there is hope youll get back to normal too . So Im sure you will get there. Lifestyle factors such as heavy smoking and drinking or a poor diet over a prolonged period can also lead to low B12 levels or deficiency. Some or all of it can be reversed and that's the good news. Since B12 is a water-soluble vitamin, its generally considered safe, even at high doses. A few symptoms of B12 deficiency include: Conditions of the small intestine (Crohns disease), anemia, fatigue, constipation, poor balance, memory loss, shortness of breath, and more. Choosing a selection results in a full page refresh. Im feeling almost normal again energy wise. I chose high-efficiency lysoformal because it's the trending vitamin these days, so I think it's better than other B vitamins. Hi Quinny99 It is not uncommon for some symptoms to appear to get worse before they get better as the B12 you are having starts repairing the damage done to your nervous system and your brain starts getting multiple messages from part of the body it had "forgotten about" or lost contact with. If youre sure the B12 was pure, then the next question would be, was the correct fluid added to the vial? I was upset b/c when I returned after the first the nurse thought I'd feel cured. I'm not convinced by the reports they provide that they have conclusive evidence of peripheral neuropathy from B6 at doses under 25mg. Wow! WebThe main reason why some people feel worse after their B12 injection is due to an increase in energy. I too felt worse at first. A neurologist recently decided to test my Vitamin B 12 levels and determined that, although I was within the normal range, I had a deficiency that may be contributing to symptoms, possibly causing my migraines. Symptoms. Vitamin B12 or folate deficiency anaemia can cause a wide range of symptoms. My GI said that I can only have it every 3 months, I cannot have it any sooner (thats the NHS for you). Sadly my much improved digestion has gone downhill again. If you get the blood results Im sure that will help. Benefits, sources & deficiencies, 9 Hidden Dangers of Taking Health Supplements, Vitamins, Supplements and Nutrition in Pregnancy. I hope you are feeling better now and things are starting to settle down for you x x x. Thank you so much!! Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. I may not be postulating this right, but the \ B12 and B9 are so inter-related. Thank you for all the information. If anything other than sterile saline was added, it may have been a preservative that you had reacted to. Posted I sometimes liken it to a badly tuned radio on which you have turned the volume up high trying to catch the programme you want when all of a sudden the signal comes in loud and clear and the blast nearly deafens you. It might explain why you felt better at first and then feel unwell again. A retest now of serum B12, once on weekly injections, will probably be unhelpful as it will be high either way. There is no set timescale as we are all different. hope this answer is helpful. So if you can get some folinic or methylfolate, that will help. Did your daughter have any abnormal hematology results? These cookies track visitors across websites and collect information to provide customized ads. A neurologist recently decided to test my Vitamin B 12 levels and determined that, although I was within the normal range, I had a deficiency that may be contributing to symptoms, possibly causing my migraines. My experience is that B12 deficiency is not well understood by some health professionals. MMA should drop once B12 is replete. Anemia, when you don't have enough red blood cells. Can give similar symptoms to low B12, you might be deficient in both. I too experienced this, despite my gp telling me I would feel like a new woman after a few shots I felt worse. WebI began B-12 injections 2 times per week and within one week noticed a dramatic improvement in my energy levels. I have pernicious anemia is that what u have too? I feel the same I don't feel any better my doctor thinks it's in my head as I should feel so much better I feel soow, How are you feeling now? Thereafter, 100 mcg should be injected once a month for life. There are lots of potential causes of B12 deficiency. e u just give it to yourself in the fat of your stomach and it is absolutely painless and that is coming from someone who does not like needles i was terrified but after they administered my first shot at my first appointment it was not bad at all. Hydroxocobalamin is usually the recommended option as it stays in the body for longer. I have had crying episodes that I did not have beforeso this vitamin injection did me little good. Dietary-caused anaemia and B12 deficiency may take fewer injections to deal with the common fatigue and superficial symptoms. Muscle aches, constant pain & horrible fatigue. Chills, night sweats, fever, or hot flushes. Avoid irritated skin and blood vessels. Almost immediately, I developed swollen, painful sores that were identified as cystic acne breakouts by a dermatologist. The original poster's symptoms sound like normal B12 neurological recovery symptoms to me - similar to those experienced by me and many others here. Hi there, Im in the same boat with B12 injection. Nitric oxide is a gas we make , Blood: THC from edibles can be detected for 3 to 4 days in blood. So Im about to go for my first injection (as I have them once every 3 months). I had forgotten what it was like to have this kind of energy. Is vitamin B12 good for energy? I just need to sort myself out as its stopping me from going to University lectures and stuff like that. Has some overseas members. WebSerious vitamin B12 deficiency may result in anemia, stomach problems, and nerve damage. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". We cannot be held liable for our third-party providers. I get tired and short tempered. id be more worried about whats causeing these symptoms ? Provision of B12 allows repair to begin but the actual healing process itself is open-ended (months to years) depending on how much damage has been done. Always speak to your doctor before acting and in cases of emergency seek Feeling worse after B12 Injections. Its tough. Thank you so much!! Clinics charge as much as $250 per B12 shot. Anyone at any age, can become B12 deficient. Older adults who have a vitamin B12 deficiency will likely have to take a daily B12 supplement or a multivitamin that contains B12. Can you have any reactions or side effects from vitamin B12 injections? as being in breach of those terms. WebThis causes symptoms like muscle weakness, fatigue, appetite loss, feelings of unwellness, irritability, numbness, etc. Unanticipated benefits of more energy, eliminated binging behavior, and more focused/alert. "What You Need to Know About Pernicious Anaemia and B12 Deficiency" by Martyn Hooper. People diagnosed with anaemia (including iron deficiency anaemia, sickle cell anaemia and thalassaemia). Youre not alone. I began B-12 injections 2 times per week and within one week noticed a dramatic improvement in my energy levels. Cases of allergic reactions to hydroxy B12 with tolerance to cyano B12 were recorded. It could have been worsea severe vitamin B 12 deficiency can lead to deep depression, paranoia and delusions, memory loss, incontinence, loss of taste and smell, and more. Zero cases. We can all agree that B6 is a possible cause of peripheral neuropathy but based on the limited information here, everything points to the neuropathy being from a B12 deficiency, not a B6 overdose. Many people experience this issue, yet it is often misunderstood. It's quite common for forum members to report that their symptoms get worse for a while before starting to get better. Our injectable B12 is methylcobalamin, which is an active, native form with no recorded anaphylactic reactions in medical literature. this seems to be quit good, has good results already, and is easy to take u just give it to yourself in the fat of your stomach and it is absolutely painless and that is coming from someone who does not like needles i was terrified but after they administered my first shot at my first appointment it was not bad at all.Read More Read Less, Routine test showed a B12 deficiency that was unreadable by local labs. Your GP or nurse will give the injections. Thanks to its role in energy metabolism, vitamin B12 might reduce your chance of fatigue. As with any advice, treatment or recommendation given by a physician or other healthcare provider, I urge everyone to do their own research, accurately report symptoms and/or satisfaction/tolerance, and determine what is best for you, your health, and your situation.Read More Read Less. People with a family history of pernicious anaemia. feel just as tired as usual. This is because it is important for energy metabolism, which may interrupt your sleep if taken at night. : An Epidemic of Misdiagnoses" by Sally Pacholok and JJ. Many B12 deficient folks (especially those with pernicious anemia) have trouble clearing out the cyanide. i will post further progress with this drug as my treatment furthers with it. A very different experience to the loading doses. It just seems that the doctor doesnt take all of this seriously or thinks that I am making all of it up. I can tell when I need my shot. Why are beauticians giving B-12 injections? Symptoms I had after loading were spots everywhere , dizziness, nausea and fogginess in head which were all more extreme than before loading. They include the following: Vegetarians, vegans and people eating macrobiotic diets. i will post further progress with this drug as my treatment furthers with it. I do think the high folate w/ the (absent?) But I feel like I could try it in the next couple of weeks. At this point, I have not finished my monthly injections and do not plan on doing so. Since he seemed initially to benefit from this treatment, it is still possible that he was deficient. The cookies is used to store the user consent for the cookies in the category "Necessary". Dont store them inside a kitchen cabinet or the refrigerator. Despite the numerous processes in which vitamin B12 is involved, theres little evidence to suggest that it has any influence on weight gain or loss. I don't doubt in the least that juanpablo is suffering from something, but I'd be surprised if B12 had anything to do with it. Typically, our patients experience positive effects between 24-72 hours after the treatment. We have many repeat customers, so it must tell you something about how rare a true allergy is. Im experiencing exactly the same as you. It does get better, just make sure you get the next 2 or 3 monthly top up jabsI've had to pay privately for mine as nhs seem to think a reading of 305 is okwhen it's defiantly not. If you order your B12 shots anywhere else, make sure it comes from a certified lab that follows stringent pharmacy regulations. Been taking this when B12 levels were below 120. Pernicious Anemia is a permanent condition with no known cure. Rhinitis (chronic sneezing or a congested, drippy nose). I think the damage takes longer than the healing, maybe? There is a light at the end of the tunnel! Contact PAS for details. and Privacy Policy and steps will be taken to remove posts identified Someone once described it to me as the nerves starting to wake up after being starved of B12 for so long. Keep in mind when I got the ECG I was having a severe panic attack and had a heart rate of around 110 so not sure if this tachycardia caused by anxiety resulted in this assessment (I think it's an automated assessment from the machine) . Next link about causes is from a Dutch B12 website. Regular provision of intravenous B12 in such circumstances is necessary for the continuation of life - its not a band-aid. If the b12 FERRITEN folate needs to be in balance us FERRITEN 40 to low ? Just a thought, have you had your ferritin checked? B6 overdose is real and can be dangerous but it's a lot harder to get in trouble with B6 than many people (including doctors) seem to think. People whove undergone any gastric and/or intestinal surgery, including bariatric surgery for weight loss purposes (Gastric bypass). Hypophosphatemia after an iron infusion is quite rare. Thank you again. People who regularly use proton-pump- inhibitors. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. So I will follow Ur story and send U a big hug as I fully understand how U feel x. In the complementary medicine realm B12 is probably one of the safest things you could take. But, it feels equally bad while that happens (my experience, too) or maybe worse. Among many symptoms attributable to low B12, I have experienced the following over the years: Tongue Burning Numbness of Limbs Tingling of Limbs Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Avoid any blood thinning medication. Creatine. If you were a recovering alcholic, you'd have withdrawl symptoms, right? I just had my first shot after the loading doses three days ago. Your body is damaged and will likely feel worse before you're all better. I too suggest you make sure your iron levels are ok and also maybe ask for your throid functions to be checked if you havent had that done. Can you please let me know the problem is occurring due to this dose. Unless someone is getting B6 over 25mg a day for quite a long time, its highly unlikely for adverse effects to be seen. The easiest site when self-administering an IM injection is the middle third of the vastus lateralis muscle of the thigh. No negative side effects, however I am taking this in addition to a progesterone supplement due to earl. Applying a cold compress for 5 to 10 minutes after your injection can limit swelling and redness. That will take a good six months to one year - even longer in some. The best way to prevent feeling worse after a B12 injection is by starting with small doses and gradually increasing them over time. Martyn Hooper is the chair of PAS (Pernicious Anaemia Society). As I continued to get the shots it new here and new to the world of b12 deficiency,lucky as I am I also have vit d deficiency too so the 4th/5th I was feeling slightly better, getting more done during the day. How often should I get B12 shots for weight loss? I mis-read the message. I went into the walk-in Important: Patients withLeberhereditary optic neuropathy should not take methyl B12shots. 2005 - 2023 WebMD LLC, an Internet Brands company. Prices are for cash paying customers only and are not valid with insurance plans. Injection site reactions are usually mild when they do occur. Analytical cookies are used to understand how visitors interact with the website. It is harmless and often used in ultra-high doses. I've never seen B12 listed as a cure for eczema but if it wasn't what cured her skin issues it was awfully coincidental. I was found to have "ventricular ectopics" - which, although I had 4,000 episodes in that period, was not dangerous and went away eventually a few months later without needing treatment. I am 40 years old and was tired all of the time. It Sounds like B6 overdose. If its none of the things hes testing, he said its probably anxiety. It just goes to show that the 'B12 deficiency is unlikely in someone so young' is probably right most of the time, but not always. Vitamin B12 or folate deficiency Usually a dose of 0.25-0.5 mg/kg is sufficient. All our partner labs hold UKAS, ISO17025 / ISO15189 / IS013485 accreditations. I hope you start to feel better soon and that you have a kind doctor who listens to you. Ive been to the doctors about the see symptoms and I need to have another blood test. You're right Technoid. I have B6 toxicity, P.A. Untreated B12 deficiency is potentially life-threatening. You need to query it and get it re-tested. Who can and cannot have it Having your injection Side effects Pregnancy, breastfeeding and fertility Having it with other medicines and herbal supplements Common questions Related conditions. If you get b12 shots, you may experience side effects like dizziness, nausea, and fatigue. Muscle imbalances. At this point, I have not finished my monthly injections and do not plan on doing so. Things I notice: more energy, improved stamina at the gym and on the field, increased appetite, results from workouts improving, mood improved, restful sleep, and I have lost a few pounds and kept it off easily. Plus get the inside scoop on our latest content and updates in our monthly newsletter. But everyone reacts to everything differently. Basically by pervious B12 deifciency symptoms just mych more intense. Non-existent B12 has to be a misprint or the test was not done. Some links may have details that could be upsetting. We want the forums to be a useful resource for our users but it is important to remember that the forums are You would have to be repeatedly going above the tolerable upper intake limit every day for quite a long time before you would run into issues. Most absorption problems aren't treatable but a few are - notably h pylori infection - which would mean that once that has been dealt with you would be able to absorb B12 from your diet so wouldn't need maintenance shots for life. I am an older person over 70 but I was still surprised by a negative reaction that I had previously not experienced. Answer From Brent A. Bauer, M.D. 6 years ago, Also, make sure it doesnt contain benzyl alcohol, or at least check that youre not sensitive to it. Based in Wales, UK. I was on prescribed folate but when that finished I now take a multi vitamin every day . Initially, replacing B12 will lead to a huge increase in the production of blood cells and platelets (which occurs in the bone marrow) and can lead to rapid depletion of folate and iron stores; this can then limit the expected recovery of Haemoglobin. I can't concentrate and keep forgetting what I am talking about. But Im just not well all the time, constantly in pain. She had been diagnosed as iron deficient several years before but her doctor at that time didn't test her B12 level. Though rare, this reaction can cause muscle cramping, PearlH -- not sure if you'll see this, but B6 lowers FOLATE. Ive also experienced prolonged pains in my upper left part of my stomach, which happens every so often. Extreme muscle pains, tingling, tinnitus, dizziness, fatigue, twitching, cramps, actually often feel like I have the flu but no fever. Any advice is appreciated. The sudden rush of energy can be overwhelming for some people, leading to fatigue and headaches that last for several days after the injection. Heres a case of two female pernicious anemia patients who had negative reactions to hydroxy B12 shots. A one-ounce portion (roughly a quarter cup) of raw . My general practitioner said to get back on the shots after a couple of years of my not taking them. I heard that u can feel worse after injections for a while then it improves which i really hope it does i just want to be back to full energy like i was a few days after injections. Avoid touching the injection site for 6 hours after your treatment. Many of the reported side effects of vitamin B12 injections are consistent with the diseaseitself. Skip dairy for now, or take lactase supplements. No prescription needed. My current experience is not great, unless you can define nausea as "great." Major confusion, depression, and fatigue. It is a synthetic form of B12 that contains cyanide attached to the B12. I seem to notice that I get sick after receiving the shot, which is given once a week. Anaemia is where you have fewer red blood cells than normal or you have an abnormally low amount of a substance called haemoglobin in each red blood cell. B12 may be injected into a muscle or under the skin at 100 mcg daily for a week, every other day for another week, and then every three or four days for a month. And the medicines i take may have interferred with it is my only guess as to why this happened. My doctor recommended these injections as I've gone 100% vegan diet about a year ago. It helps your body metabolize carbs, proteins, and fats, which your body converts into energy. Things I notice: more energy, improved stamina at the gym and on the field, increased appetite, results from workouts improving, mood improved, restful sleep, and I have lost a few pounds and kept it off easily. Difficulty breathing or swallowing. The cost for Vitamin B12 injectable solution (1000 mcg/mL) is around $90 for a supply of 25 milliliters, depending on the pharmacy you visit. For example, heres a case of a 67 year old man who reacted to a hydroxy B12 shot that contained 1.5% benzyl alcohol. There is a PAS support group in Chicago area . Store the vials in a cool room. Ideal for Vegans/Vegetarians with normal healthy stomachs. She told me that many patients tell her they feel tired as they get nearer to their B12 shot been due. At first, youll have these injections every other day for 2 weeks or until your symptoms have started improving. Anyone staying below 25mg of B6 a day is unlikely to run into problems, let alone neurological symptoms (which are only seen at 100mg/day). When your body receives the B12 shot, it begins to absorb more of the nutrient than usual, which can cause a spike in energy levels. WebPain/redness at the injection site, mild diarrhea, itching, or a feeling of swelling all over the body may occur. Diet-related If your vitamin B12 deficiency is caused by a lack of the vitamin in your diet, you may be advised to take Ive started a series of weekly 1mg methyl B12 shots, and none of my symptoms have improved. I dont know. My B12 Levels were at 172, and the doctors kept insisting that it was my diet that was causing this (baring in mind I eat meat and everything fortified with B12). Step 1. I keep a diary of my symptoms and take other vitamins and minerals such as folic acid, iron+vitamin c and eat potassium rich foods. I am still tired (I take iron tablets 3 times a day). Since B12 shots are injected intramuscularly bypassing the digestive process, they start to work immediately. i know that your question is 4yrs old and i hope youve found the answer if not , latest findings on B6 toxicity does seem to match most of your symptoms. If your serum B12 level was 0 then I'm guessing you feel really ill. All rights reserved. Are pumpkin seeds good for you calories? Eating bananas and trying a very healthy diet but the increase of symptoms and pain make me very, very insecure and scared. I haven't felt much of a change in my migraines, but have noticed that I just haven't been feeling well overall on a day to day basis. Me too, feeling even worse than before the injections. Heart palpitations: this could be anxiety - one of the many symptoms of B12 deficiency. How are you managing things now, Diagnosis with PA a month ago & had my 6 loading injections last one last week, Feel awful too , worse my b12 was 150 & serum iron 8, Also now started, really hope things improve soon. That being said, the conversion of severe anemia to normal production of red blood cells could temporarily lead to low potassium levels and high platelet count. It comes 100% pure, no additives or preservatives whatsoever. 11 users are following. Feeling awful for 2 weeks now after only second shot. But back then I did not realise how the vitamins work together and was only taking folic acid. I hope you get the answers youre looking for too! Registered in England and Wales. "Could it Be B12? (And all I have is the low B12) Didn't work like that for me! How long does it take to recover from vitamin B12 deficiency? Folate could be a problem too. Overdosing with B12 is not very likely, yet too frequent administration may cause side effects like nausea, skin swelling and redness (on the injected spot), and similar. When patients have suffered a B12 deficiency through a disease like pernicious anemia, then quite often the disease is only diagnosed at the end stage. Cited by 25 Although measurement of vitamin B12 levels is the gold standard for the diagnosis of B12 deficiency some reports do exist concerning difficulties in its assay. I do hope you get to the bottom of this. I had plenty of this. 5% discount coupon code: AID8235. a 89 year old lady developed signs of malaise, collapse and vomiting. H2 blockers, antacids, Metformin, and related diabetes drugs, or other medications, or infections such as h-pylori that can interfere with B12 absorption. Anaphylactic reactions (strong allergic reactions) have been reported, though very rarely, to either cyanocobalamin, hydroxocobalamin, or both: Allergy to vitamin B12 is uncommon. These usually develop gradually but can worsen if the condition goes untreated. At first, you may need to have the injection a few times a week to boost your levels of vitamin B12. But a single report doesnt exact make for a conclusive case - there are many causes of peripheral neuropathy - were they all excluded in this single case leaving only B6 as the cause? Whats more, reactions are more likely to be the result of additives rather than the B12 itself. Sharp stabbing pains in the hands after B12 repletion is normal/expected due to nerve repair starting omce treatment begins. Living With Pernicious Anemia & B12 Malabsorption. Today I am hurting all over. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. However, its important to know what your levels are, after all, vitamin B12 deficiency can cause damage to your nerves and affect brain function. No negative side effects, however I am taking this in addition to a progesterone supplement due to early in life hysterectomy. I started receiving B12 injections (9 so far). Lastly, Ive been waking up from having leg cramps and my feet feel like theyre wanting to cramp constantly. They can be used intermittently and are a popular rejuvenation therapy for exhaustion, burn out, migraines and of course post-party nausea! Where is the best place to give a B12 injection? Most documentation papers indicate you might experience any of these: However, people fail to recognize one thing. Thanks. The problem with a retest at this point is that after 6 injections, the B12 level will likely be elevated and it will be very difficult to know what the original value would have been. Thank you so much. What foods is high in nitric oxide? All our partner pharmacies are registered with GPhC. Tingling, numbness, weakness, and balance problems. The author of the study, Dr. Rosa Caballero, said that the allergens involved in vitamin B12 reactions is likely to be a hapten..
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